解説記事 Earozoru Kenkyu, 29 (3), 200-205 (2014)
吸入によるPM2.5の体内取り込みについて考えること
福津久美子 1*
Some Thoughts on the Particle Size of Inhaled PM2.5
Kumiko FUKUTSU 1*
Abstract
PM2.5の健康影響を考える時、濃度や化学成分と同様に、吸入粒子の粒径分布は重要な因子である。粒径分布は呼吸器内での全体および部位別沈着に大きく影響する。しかし、PM2.5の規制は粒径や成分に言及することなく重量濃度（μg m-3）に基づいている。本報では、PM2.5の粒径と呼吸器内部位別沈着との関係の議論を通じて、吸入放射性粒子の線量評価のためのICRP Publ.66呼吸気道モデルを用いて粒径の重要性を述べる。
When we consider the health effect of PM2.5, the size distribution of inhaled particle is the important factor as well as the concentration and the chemical component. The size distribution significantly alters the total and regional deposition in the respiratory tracts. However, regulations of PM2.5 are based on the mass concentration (μg m-3) without mentioning the particle size and components. In this report, I present the importance of particle size using ICRP Publ.66 respiratory tract model for dose assessment of inhaled radioactive particles through the discussion on the relationship between particle size of PM2.5 and regional deposition in the respiratory tracts.